TY - JOUR
AU - KAMINSKI, EDWARD, J.
AB - Abstract Toxic Effects of Cu Implants on liver. KELLER, J. C, AND KAMINSKI E. J. (1984). Fundam. Appl. Toxicol. 4, 778–783. In an effort to identify possible systemic effects due to dissolution of Cu from the experimental use of dental amalgam specimens of pure Cu and several dental amalgams containing various concentrations of Cu were implanted into the peritoneal cavity of rats for 4 weeks. Concentrations of Cu in the liver varied from 33.3 to 156.2 μCu/dry g of liver tissue after implantation of the Cu-containing amalgams. Histopathological changes in the liver confirmed the presence of Cu within the tysosomes of hepatocytes. The histopathological and chemical changes in the liver after implantation indicated the need for subsequent investigations of long-term systemic toxicity to the use of Cu-containing implants This content is only available as a PDF. Author notes 1Presented in part at the 1983 Annual Meeting of the American Association for Dental Research Meeting, Cincinnati, Ohio. Supported by NIDR/NIH Training Grant DE07042. 2Present address: Department of Materials Science, Medical University of South Carolina, Charleston, S.C. 29425. To whom correspondence should be addressed. © 1984 by the Society of Toxicology
TI - Toxic Effects of Cu Implants on Liver
JF - Toxicological Sciences
DO - 10.1093/toxsci/4.5.778
DA - 1984-10-01
UR - https://www.deepdyve.com/lp/oxford-university-press/toxic-effects-of-cu-implants-on-liver-pECmaKksk1
SP - 778
EP - 783
VL - 4
IS - 5
DP - DeepDyve
ER -