TY - JOUR
AU - 
AB - Abstract. We acquired in vivo images of the human optic nerve head (ONH) using an adaptive optics—optical coherence tomography (AO-OCT) system. In order to improve imaging of the lamina cribrosa in the ONH with high lateral resolution and sensitivity, we implemented a complex conjugate artifact-free Fourier domain OCT (Fd-OCT) acquisition scheme with a reference arm-based phase shifting method. This allowed positioning of the lamina cribrosa structures near the zero path length difference where AO-OCT imaging achieves highest sensitivity. Implementation of our complex conjugate artifact removal (CCR) method required constant phase shifts between consecutive axial scans (A-scans), generated by continuous beam path-length changes from offsetting the pivot point of the scanning mirror placed in the reference arm. Fourier transform along the transverse axis and a filtering algorithm allowed reconstruction of CCR AO-OCT images. The suppression ratio of the mirror artifact was approximately 22 dB (at 18,000 A-scans per second acquisition speed) with a paperboard test target and an optimum phase-shift value. Finally, we reconstructed the three-dimensional structure of human ONH with enhanced depth range and sensitivity using CCR AO-OCT.
TI - Complex conjugate artifact-free adaptive optics optical coherence tomography of in vivo human optic nerve head
JF - Journal of Biomedical Optics
DO - 10.1117/1.JBO.17.12.126005
DA - 2012-12-01
UR - https://www.deepdyve.com/lp/spie/complex-conjugate-artifact-free-adaptive-optics-optical-coherence-oI9ig4B9wP
SP - 126005
EP - 126005
VL - 17
IS - 12
DP - DeepDyve
ER -