TY - JOUR AU - HECKMATT, J AB - British Medical Bulletin (1980) Vol. 36, No. 2, pp. 139-144 MANAGEMENT OF MUSCULAR DYSTROPHY V Dubowitz & J Heckmatt subsequent progress of the case ascertained; and in the case of one patient the symptoms were very slight, and, as recorded, not very decisive." Gowers might have been commenting on some similar claims of therapeutic success appearing in learned MANAGEMENT OF MUSCULAR medical journals almost a century later. DYSTROPHY 1 Therapeutic Trials Pharmacological and Physical Aspects Much effort and expense can be dissipated in setting up controlled therapeutic trials in order to refute claims which have V DUBOWITZ MD PhD FRCP no rational basis. The initial onus is thus on the authors of pilot J HECKMATT MB ChB MRCP studies to substantiate their claims in an initial trial before large-scale studies are set up. It would be helpful if authors and Department of Paediatrics and Neonatal Medicine journal editors were more critical before publishing preliminary and results on potential therapies in incurable conditions. Jerry Lewis Muscle Research Centre There is the additional problem that once a potential "cure" is Hammersmith Hospital, London published, particularly in the lay press, it can be difficult, for example, to convince the parents of a TI - MANAGEMENT OF MUSCULAR DYSTROPHY: Pharmacological and Physical Aspects JO - British Medical Bulletin DO - 10.1093/oxfordjournals.bmb.a071629 DA - 1980-05-01 UR - https://www.deepdyve.com/lp/oxford-university-press/management-of-muscular-dystrophy-pharmacological-and-physical-aspects-nuj70WZHv2 SP - 139 EP - 144 VL - 36 IS - 2 DP - DeepDyve ER -