TY - JOUR
AU - Pollock, A V
AB - Seventy-one patients with peritonitis due to perforation of the appendix were treated by preoperative rectal metronidazole, appendicectomy and omission of skin closure. They were then randomized to have either no further antibacterial treatment, or rectal metronidazole twice-daily for 5 days. No major wound infections occurred, but 8 patients developed intraperitoneal abscesses. In addition, I died of a pulmonary embolus and 1 required further laparotomy for intestinal obstruction.Patients in the 5-day-metronidazole group suffered fewer intraperitoneal abscesses and less pyrexia, but the differences did not achieve statistical significance. This series shows a considerable improvement over a previously published series in terms of morbidity, duration of pyrexia and length of hospital stay.
TI - The management of the perforated appendix: A controlled clinical trial
JF - British Journal of Surgery
DO - 10.1002/bjs.1800690905
DA - 1982-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-management-of-the-perforated-appendix-a-controlled-clinical-trial-ndjwg0KP5b
SP - 510
EP - 512
VL - 69
IS - 9
DP - DeepDyve
ER -