TY - JOUR AU - Smith, Michael, J. AB - Abstract Therapy for endocarditis due to Pseudomonas aeruginosa is complicated by the emergence of resistance during therapy, lack of universally available synergistic antimicrobial agents, and unacceptably high morbidity and mortality rates. The authors report a case of aortic valve endocarditis due to P. aeruginosa in which resistance to piperacillin developed during combined therapy with tobramycin. Bacteriologic cure was obtained with a combination of imipenem/cilastatin and tobramycin. The authors review six other cases of P. aeruginosa endovascular infections treated with imipenem. This content is only available as a PDF. Author notes * Infectious Diseases Section, Washington University, St. Louis, Missouri. © 1992 by The University of Chicago TI - Treatment of Endocarditis Due to Pseudomonas aeruginosa with Imipenem JF - Clinical Infectious Diseases DO - 10.1093/clinids/14.1.353 DA - 1992-01-01 UR - https://www.deepdyve.com/lp/oxford-university-press/treatment-of-endocarditis-due-to-pseudomonas-aeruginosa-with-imipenem-nYaYOR7F0T SP - 353 EP - 354 VL - 14 IS - 1 DP - DeepDyve ER -