TY - JOUR
AU - Mašek, Karel
AB - THE JOURNAL OF INFECTIOUS DISEASES • VOL. 123, NO.6· JUNE 1971 © 1971 by the University of Chicago. All rights reserved. Release of S-Hydroxytryptamine and Morphological Changes in Blood Platelets Induced by Mucopeptide of Streptococcal Cell Walls Helena Raskova, Milos Rye, JiH Rotta, From the Institute of Pharmacology, Czechoslovak Academy of Sciences, and the Institute of and Karel Masek Hygiene and Epidemiology, Prague, Czechoslovakia Mucopeptide isolated from the streptococcal cell washed bacteria were suspended in distilled water; wall has pronounced biological activities in mam­ the volume was 1 % of that of the original culture. mals. A strong pyrogenic response as well as The mechanical disruption of cells was performed marked hemodynamic changes in rabbits have in a Braun disintegrator with use of Ballotini no. been described [1-4]. Some features of the fe­ 12 glass beads. The cell walls harvested by centrif­ ver produced resemble those provoked by endo­ ugation at 4,000 g were washed and treated with toxin of gram-negative bacteria; however, the ribonuclease, deoxyribonuclease, and trypsin; the mechanism of the febrile response induced by mu­ enzyme-treated preparation was dialyzed and ly­ copeptide is probably different from that produced ophilized. The extracted group-specific carbohy­ by endotoxin [2]. The 
TI - Release of 5-Hydroxytryptamine and Morphological Changes in Blood Platelets Induced by Mucopeptide of Streptococcal Cell Walls
JO - The Journal of Infectious Diseases
DO - 10.1093/infdis/123.6.587
DA - 1971-06-01
UR - https://www.deepdyve.com/lp/oxford-university-press/release-of-5-hydroxytryptamine-and-morphological-changes-in-blood-nCaUlg4LfK
SP - 587
EP - 594
VL - 123
IS - 6
DP - DeepDyve
ER -