TY - JOUR AU - Fink, James B. AB - CRITICAL CARE/RESPIRATORY CARE Aerosol Drug Delivery During Mechanical Ventilation: Devices, Selection, Delivery Technique, and Evaluation of Clinical Response to Therapy Arzu Ari, PhD, RRT, PT, CPFT, FAARC, and James B. Fink, PhD, RRT, FAARC, FCCP and clinical response to therapy to assure optimal patient Abstract: Aerosolized medications are increasingly being used in benefit, well-being, and safety during inhalation therapy. ventilator-dependent patients. There are many issues with selection and use of aerosol delivery devices in patients receiving ventilator support. The purpose of this paper is to explain potential problems associated AEROSOL DEVICES with aerosol devices, delivery technique, and clinical response to Two types of aerosol devices are used for aerosol drug therapy to assure patient well-being and safety during inhalation delivery to ventilator-dependent patients: (1) nebulizers and (2) therapy. pressurized metered dose inhalers (pMDIs). Types of nebu- lizers used for the treatment of intubated and mechanically Key Words: nebulizers, metered-dose inhalers, aerosols, drug deliv- ventilated patients are jet nebulizers (JNs), ultrasonic nebu- ery, optimum technique, mechanical ventilation lizers (UNs), and vibrating mesh nebulizers (VMNs). Figure 1 (Clin Pulm Med 2015;22:79–86) shows illustrations of aerosol devices used for the treatment of ventilator-dependent patients. any formulations, both solutions and suspension, such as TI - Aerosol Drug Delivery During Mechanical Ventilation Devices, Selection, Delivery Technique, and Evaluation of Clinical Response to Therapy JO - Clinical Pulmonary Medicine DO - 10.1097/CPM.0000000000000085 DA - 2015-03-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/aerosol-drug-delivery-during-mechanical-ventilation-devices-selection-n0a0jUZQAx SP - 79–86-79&ndash EP - ndash;86-79–86 VL - 22 IS - 2 DP - DeepDyve ER -