TY - JOUR AU - Dooley, T. P. AB - Arch Dermatol Res (2000) 292 : 469–471 © Springer-Verlag 2000 SHORT COMMUNICATION E. S. Robinson · G. B. Hubbard · T. P. Dooley Metastatic melanoma in an adult opossum (Monodelphis domestica) after short-term intermittent UVB exposure Received: 26 November 1999 / Revised: 20 March 2000 / Accepted: 24 March 2000 Key words Malignant melanoma · UVB · Monodelphis During suckling exposure, inevitably the ventral sur- domestica · Animal model faces of the body, feet and tail of the mother are also ex- posed to UVB. One nursing mother (C4390) developed a melanocytic lesion on the ventral surface of the tail which eventually progressed to a malignant melanoma with There is now compelling epidemiological evidence that lymph node involvement. The affected female produced a exposure of humans to the ultraviolet B (UVB) compo- total of six litters, three of which were assigned to the nent in solar radiation is a risk factor for cutaneous malig- UVB protocol over a period of about 7 months. She was nant melanoma, and animal models have been sought to the only nursing mother out of 38 exposed to between study the etiology of this serious human disease [1]. A three and six regimens that TI - Metastatic melanoma in an adult opossum (Monodelphis domestica) after short-term intermittent UVB exposure JF - Archives of Dermatological Research DO - 10.1007/s004030000145 DA - 2000-09-25 UR - https://www.deepdyve.com/lp/springer-journals/metastatic-melanoma-in-an-adult-opossum-monodelphis-domestica-after-mk2zGFrJIF SP - 469 EP - 471 VL - 292 IS - 9 DP - DeepDyve ER -