TY - JOUR AU1 - Zhi, Tiantian AU2 - Zhou, Zhou AU3 - Huang, Yi AU4 - Han, Chengyun AU5 - Liu, Yan AU6 - Zhu, Qi AU7 - Ren, Chunmei AB - Planta (2016) 244:557–571 DOI 10.1007/s00425-016-2530-6 ORIGINAL ARTICLE Sugar suppresses cell death caused by disruption of fumarylacetoacetate hydrolase in Arabidopsis 1 1 1 1,2 1 • • • • • Tiantian Zhi Zhou Zhou Yi Huang Chengyun Han Yan Liu 1 1 Qi Zhu Chunmei Ren Received: 13 January 2016 / Accepted: 11 April 2016 / Published online: 20 April 2016 Springer-Verlag Berlin Heidelberg 2016 Abstract genes cell-wall invertase 1 and alkaline/neutral invertase Main conclusion Sugar negatively regulates cell death G, was up-regulated in the sscd1 mutant, however, this up- resulting from the loss of fumarylacetoacetate hydro- regulation could be repressed by sugar. In addition, a high lase that catalyzes the last step in the Tyr degradation concentration of sugar attenuated cell death of Arabidopsis pathway in Arabidopsis. wild-type seedlings caused by treatment with exogenous succinylacetone, an abnormal metabolite resulting from the Fumarylacetoacetate hydrolase (FAH) hydrolyzes fumary- loss of FAH in the Tyr degradation pathway. These results lacetoacetate to fumarate and acetoacetate, the final step in indicated that (1) sugar could suppress cell death in sscd1, the tyrosine (Tyr) degradation pathway that is essential to which might be because sugar supply enhances the resis- animals. Previously, we first found that TI - Sugar suppresses cell death caused by disruption of fumarylacetoacetate hydrolase in Arabidopsis JF - Planta DO - 10.1007/s00425-016-2530-6 DA - 2016-04-20 UR - https://www.deepdyve.com/lp/springer-journals/sugar-suppresses-cell-death-caused-by-disruption-of-mKVJU2eAsV SP - 557 EP - 571 VL - 244 IS - 3 DP - DeepDyve ER -