TY - JOUR
AU - Segal, Ester
AB - Abstract Porous silicon (PSi) has emerged over the past decade as a promising biomaterial for nanomedicine in general and cancer nanomedicine in particular. PSi offers a unique combination of properties, including large surface area and porous volume, biocompatibility, degradability in vivo into non-toxic silicic acid species, as well as its wealth of intrinsic optical properties (e.g., luminescence, photonic). This arsenal of properties together with the ability to tailor the PSi nanostructure and surface characteristics have led to an immense research effort directed at the development of PSi-based platforms for biomedical applications. After a brief introduction of the biology of cancer and currently practiced therapies, we provide an updated review of the progress of PSi-based platforms for cancer therapy and imaging.
TI - Porous silicon for cancer therapy: from fundamental research to the clinic
JF - Reviews in Chemical Engineering
DO - 10.1515/revce-2015-0001
DA - 2015-06-01
UR - https://www.deepdyve.com/lp/de-gruyter/porous-silicon-for-cancer-therapy-from-fundamental-research-to-the-lrLzWeOhu3
SP - 193
VL - 31
IS - 3
DP - DeepDyve
ER -