TY - JOUR AU - Russell, Harold AB - THE JOURNAL OF INFECTIOUS DISEASES. VOL. 156, NO.5. NOVEMBER 1987 © 1987 by The University of Chicago. All rights reserved. 0022-1899/87/5605-0029$01.00 Lyme Disease in Japan and Its Possible any antibiotic therapy. Over the next 10 months the patient re­ Incriminated Tick Vector, Ixodes persulcatus mained asymptomatic and had no arthritic, cardiac, or neuro­ logical abnormalities. The tick removed from the patient was iden­ tified as a female I persulcatus and is considered to be a possible COLLEAGUEs-Lyme disease is a complex multisystem disorder vector in this case. caused by a tick-borne spirochete, Borrelia burgdorferi. The dis­ Recent isolation of R burgdorferi and the development of tests ease usually begins with a characteristic skin lesion, erythema for antibodies to it promise to improve diagnostic accuracy [2, chronicum migrans (ECM), that may be followed by neurologi­ 3]. In these earlier studies an ELISA for diagnosis of Lyme dis­ calor cardiac abnormalities and is often followed by arthritis. ease was less sensitive in patients with ECM alone, and cross­ Over the past 10 years, Lyme disease has been noted in the north­ reactivity occurred with sera from patients with other spiroche­ eastern, midwestern, and western United States; in a number of tal TI - Lyme Disease in Japan and Its Possible Incriminated Tick Vector, Ixodes persulcatus JF - The Journal of Infectious Diseases DO - 10.1093/infdis/156.5.854 DA - 1987-11-01 UR - https://www.deepdyve.com/lp/oxford-university-press/lyme-disease-in-japan-and-its-possible-incriminated-tick-vector-ixodes-l70LE257cu SP - 854 EP - 854 VL - 156 IS - 5 DP - DeepDyve ER -