TY - JOUR AU - Meyer, K. F. AB - JOUR. INFECT. DIS., VOL. 74, No.1 THE BEHAVIOUR OF VIRULENT AND AVIRULENT P. PESTIS IN NORMAL AND IMl\1UNE EXPERIMENTAL ANIMALS E. JA WETZ* AND K. F. MEYER From the George Williams Hooper Foundation for Medical Research, University of California, San Francisco, California The technic of bacteriological autop­ ous intervals, these authors were unable sies, inaugurated by Wyssokowitsch in to recover avirulent plague organisms 1886 and perfected by the group at the by culture or subinoculation. Bablet, Danish Serum Institute under the lead­ Girard and Robie" made a study of the ership of Orskov.! has contributed much spleen hypertrophy following vaccina­ to the understanding of the mechanics tion with EV, and described the histolog­ of infections. Apart from clarifying the ical appearance of granulation tissue route of the infective agent in a number developing on the 7th day and disap­ of bacterial and virus diseases, this tech­ pearing slowly around the 12th to 20th nic has also given results elucidating the day. These authors report no bacterio­ different behaviour of normal and im­ logical examinations except the finding mune animals" and of virulent and avir­ of viable EV bacilli in the spleen on the 4 8 ulent bacterial strains. • TI - The Behaviour of Virulent and Avirulent P. Pestis in Normal and Immune Experimental Animals JF - The Journal of Infectious Diseases DO - 10.1093/infdis/74.1.1 DA - 1944-01-01 UR - https://www.deepdyve.com/lp/oxford-university-press/the-behaviour-of-virulent-and-avirulent-p-pestis-in-normal-and-immune-kG7NJSPwIr SP - 1 EP - 13 VL - 74 IS - 1 DP - DeepDyve ER -