TY - JOUR
AU - Amano, Osamu
AB - Histochem Cell Biol (2017) 148:229–238 DOI 10.1007/s00418-017-1578-0 ORIGINAL PAPER Retinoic acid regulates cell‑shape and ‑death of E‑FABP (FABP5)‑immunoreactive septoclasts in the growth plate cartilage of mice 1 2 1 1,3 Yasuhiko Bando · Miyuki Yamamoto · Koji Sakiyama · Hide Sakashita · 1,3 1,3 2 4 1 Fuyoko Taira · Genki Miyake · Shoichi Iseki · Yuji Owada · Osamu Amano Accepted: 2 May 2017 / Published online: 12 May 2017 © The Author(s) 2017. This article is an open access publication Abstract Septoclasts, which are mononuclear and spin- TUNEL reaction, RA receptor (RAR)β, and cellular reti- dle-shaped cells with many processes, have been con- noic acid-binding protein (CRABP)-II were induced in sidered to resorb the transverse septa of the growth plate E-FABP-positive septoclasts under RA excess, suggest- (GP) cartilage at the chondro-osseous junction (COJ). We ing the growth arrest/cell-death of septoclasts, whereas previously reported the expression of epidermal-type fatty cartilage-derived retinoic acid-sensitive protein (CD-RAP) acid-binding protein (E-FABP, FABP5) and localization inducing the cell growth arrest or morphological changes of peroxisome proliferator-activated receptor (PPAR)β/δ, was induced in septoclasts under VA deficiency. These which mediates the cell survival or proliferation, in septo- results support and do not conflict with our 
TI - Retinoic acid regulates cell-shape and -death of E-FABP (FABP5)-immunoreactive septoclasts in the growth plate cartilage of mice
JO - Histochemistry and Cell Biology
DO - 10.1007/s00418-017-1578-0
DA - 2017-05-12
UR - https://www.deepdyve.com/lp/unpaywall/retinoic-acid-regulates-cell-shape-and-death-of-e-fabp-fabp5-kBkdd25AR2
DP - DeepDyve
ER -