TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 274, No. 48, Issue of November 26, pp. 33888 –33897, 1999 © 1999 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. New Mammalian Selenocysteine-containing Proteins Identified with an Algorithm That Searches for Selenocysteine Insertion Sequence Elements* (Received for publication, July 2, 1999, and in revised form, August 22, 1999) Gregory V. Kryukov‡, Valentin M. Kryukov‡§, and Vadim N. Gladyshev‡¶ From the ‡Department of Biochemistry, University of Nebraska, Lincoln, Nebraska 68588-0664 and the §Laboratory of Genetic Enzymology, Institute of Biochemistry and Physiology of Microorganisms, Pushchino, Moscow 142292, Russia Mammalian selenium-containing proteins identified described in the nematode, Caenorhabditis elegans (6, 7). In- thus far contain selenium in the form of a selenocysteine terestingly, no selenoprotein genes are present in the yeast residue encoded by UGA. These proteins lack common genome of Saccharomyces cerevisiae. amino acid sequence motifs, but 3*-untranslated regions Sec-containing proteins are more common in mammals, in of selenoprotein genes contain a common stem-loop which 14 selenoproteins have been found to date (8). These structure, selenocysteine insertion sequence (SECIS) el- include four types of glutathione peroxidase (9, 10), three types ement, that is necessary for decoding UGA as selenocys- 
TI - New Mammalian Selenocysteine-containing Proteins Identified with an Algorithm That Searches for Selenocysteine Insertion Sequence Elements
JO - Journal of Biological Chemistry
DO - 10.1074/jbc.274.48.33888
DA - 1999-11-01
UR - https://www.deepdyve.com/lp/unpaywall/new-mammalian-selenocysteine-containing-proteins-identified-with-an-jzRf4t2YRz
DP - DeepDyve
ER -