TY - JOUR
AU - Wright, S E
AB - RESEARCH PAPERS PAPER CHROMATOGRAPHY OF SOME CARDIAC GLYCOSIDES AND THEIR DERIVATIVES BY JEANETTE HARRISON AND s. E. WRIGHT From the Pharmacy Department, University of Sydney, Sydney, Australia Received July 2, 1956 SEVERAL paper chromatographic systems have been used successfully for the separation of cardiac glycosidesl and some information has been obtained about the relation between the chemical structure of several glycosides and their chromatographic behaviour. Schindler and Reich- stein2 chromatographed a number of aglycones and their glycosides on formamide impregnated paper and showed the importance of an increase in oxygen content of the aglycone on the rate of travel. Heftmann and Levant3, also using formamide paper, demonstrated the influence of the degree of oxidation of the side chain at C(I0) on the rate of travel of glycosides of the strophanthidin group. They also found that acetylation of the hydroxyl groups of the aglycone increased the rate of travel, presumably because the polarity of the molecule had been reduced. Tschesche, Grimmer, and Seehofer4 sought to overcome the adsorption effects of the paper and obtain a true partition effect by using a reversed phase system of chromatography in which the organic phase was applied to the paper, and the chromatogram developed 
TI - Paper Chromatography of Some Cardiac Glycosides and Their Derivatives
JF - Journal of Pharmacy and Pharmacology
DO - 10.1111/j.2042-7158.1957.tb12258.x
DA - 1957-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/paper-chromatography-of-some-cardiac-glycosides-and-their-derivatives-jixnTe4PVQ
SP - 92
EP - 97
VL - 9
IS - 1
DP - DeepDyve
ER -