TY - JOUR AU - Iesaka, Yoshito AB - Clinical PerspectiveWhat Is New?The incidence of phrenic nerve injury (PNI) using 28‐mm cryoballoons and a short freeze strategy during the procedure, on the next day, and 1 month after, was 6.2%, 2.4%, and 1.6%, respectively.The incidence of PNI was 5.5% and 0.7% during the right superior and inferior pulmonary vein ablation.Persistent atrial fibrillation, a larger right superior pulmonary vein ostium, and deeper balloon position were associated with a higher incidence of PNI.The compound motor action potentials amplitude during the emergent deflation predicted the timing of PNI recovery.What Are the Clinical Implications?Patients at high risk for PNI can be recognized before and during the procedure.The timing of PNI recovery can be predicted during the procedure.Pulmonary vein isolation (PVI) is an established strategy for drug‐resistant atrial fibrillation (AF). Recently, cryoballoon (CB) ablation has emerged as a valid alternative to radiofrequency ablation, and a comparable efficacy and safety were demonstrated in a prospective randomized study. Nevertheless, CB ablation is associated with a significant risk of phrenic nerve injury (PNI) due to the close proximity between the phrenic nerves and balloon position. The reported incidence of PNI vary because of the different definitions, balloon generations, balloon size, freezing regimen, and protective maneuvers. Currently, TI - Characteristics of Phrenic Nerve Injury During Pulmonary Vein Isolation Using a 28‐mm Second‐Generation Cryoballoon and Short Freeze Strategy JF - Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease DO - 10.1161/JAHA.117.008249 DA - 2018-01-03 UR - https://www.deepdyve.com/lp/wiley/characteristics-of-phrenic-nerve-injury-during-pulmonary-vein-j6Ccg07H94 SP - n/a EP - n/a VL - 7 IS - 7 DP - DeepDyve ER -