TY - JOUR
AU - Graham, John M.
AB - Prader-Willi syndrome, the first known human genomic imprinting disorder, is one of the most common micro-deletion syndromes. Prader-Willi syndrome is caused by the absence of certain paternally inherited genes on the long arm of chromosome 15, resulting in a complete absence of the active copy of the genetic information in this region. It is most commonly known for its food-related characteristics of hyperphagia, food-seeking behavior, and consequent obesity. Primary care physicians play an important role in the care of children with Prader-Willi syndrome, from recognizing the presenting signs and symptoms at its various stages to understanding their unique medical, developmental, behavioral, and dietary issues. They can also serve as a valuable source of support and advocacy for the family. This article reviews the current state of knowledge about Prader-Willi syndrome and discusses up-to-date understanding of the management of this condition.
TI - Prader-Willi Syndrome: An Update and Review for the Primary Pediatrician
JF - Clinical Pediatrics
DO - 10.1177/0009922807299314
DA - 2007-09-01
UR - https://www.deepdyve.com/lp/sage/prader-willi-syndrome-an-update-and-review-for-the-primary-j4hpP3b45U
SP - 580
EP - 591
VL - 46
IS - 7
DP - DeepDyve
ER -