TY - JOUR
AU - Yoon, H‐S
AB -  Editor Melasma is a relatively common acquired symmetric hypermelanosis characterized by irregular light‐ to grey brown macules involving sun‐exposed areas. Although the precise cause of melasma is unknown, multiple factors have been implicated in the etiopathogenesis of this condition. We report a 46‐year‐old woman with a 3‐year history of brownish macules on the face ( Fig. 1 ). The lesions were irregular brown pigmentation mainly on both cheeks and cosmetically embarrassing but otherwise asymptomatic. She had no previous history of the application of topical agents to these sites and other skin diseases. Her clinical feature was consistent with melasma. She had undergone menopause at age 42 before skin lesion developed. In June 2004, she had presented to the department of general surgery with right breast mass. After some diagnostic procedures including core biopsy, the breast mass was diagnosed as infiltrative ductal carcinoma. Subsequently, she underwent resection of quadrant of right breast in December 2004, and in June 2005, she was commenced on tamoxifen (Nolvadex ® ). After a 1‐month administration of tamoxifen, she developed pigmented macules on the face. She has never had similar skin lesions before, and she has no well‐known causative factor of melasma such as 
TI - Tamoxifen‐induced melasma in a postmenopausal woman
JF - Journal of the European Academy of Dermatology & Venereology
DO - 10.1111/j.1468-3083.2009.03113.x
DA - 2009-10-01
UR - https://www.deepdyve.com/lp/wiley/tamoxifen-induced-melasma-in-a-postmenopausal-woman-iuTiTUrxS7
SP - 1199
VL - 23
IS - 10
DP - DeepDyve
ER -