TY - JOUR
AU - NATHAN, P W
AB - PAIN P W Nathan operation because of severe chronic pain, no longer had any pain; this had gone, although noxious stimuli were still felt as painful. It may then be concluded that sometimes, when the aversive components have been removed, the pain itself is also removed. It is likely that the emotional parts of pain are due to con- nexions between the regions of the cerebral cortex where the sensation of pain is felt and some aversive centres. It was P W NATHAN* MD FRCP first shown by Heath (1963) that man has a pleasure centre in the septal region similar to that of other mammals. Heath The National Hospital, London (1964) also found that when the septal region was electrically stimulated in patients with severe pain, the patients no longer felt it. Three of his patients with advanced carcinoma got 1 The peripheral nerves 2 The posterior horns immediate relief from "intense physical pain and anguish". 3 Pathways from the posterior horns to the brain The same effect was obtained by injecting acetylcholine into 4 Ascending fibres of the anterolatcral quadrant to the this region. But Gol (1967) obtained good pain relief in brain only one of six 
TI - PAIN
JF - British Medical Bulletin
DO - 10.1093/oxfordjournals.bmb.a071415
DA - 1977-05-01
UR - https://www.deepdyve.com/lp/oxford-university-press/pain-iKquon2uPV
SP - 149
EP - 156
VL - 33
IS - 2
DP - DeepDyve
ER -