TY - JOUR
AU - Shao, Xiao‐Qiu
AB - IntroductionEpilepsy surgery is a preferred option for patients with drug‐resistant focal epilepsy. Despite progress in presurgical evaluation of epilepsy, the success of epilepsy surgery has not remarkably improved over recent decades. Long‐term outcome studies suggest that the rates of seizure freedom 10 years postoperatively vary from 35% to 62%.1–3 Surgical prognosis largely relies on accurate presurgical localization of the epileptogenic zone, but it cannot be directly and definitively identified by clinical information or auxiliary examination indices. In this situation, multiple sources of clinical data should be fully utilized to define the presumptive epileptogenic zone and predict postsurgical outcome.Auras, defined as subjective ictal symptoms that precede seizures, constitute a cardinal hallmark of focal epilepsy and may have localizing and in certain cases lateralizing value in determining the epileptogenic zone.4,5 Fear is one of the affective symptoms and is common in mesiotemporal lobe epilepsy. However, although the role of temporal limbic structures, especially the amygdala, in the mediation of fearful emotion is well established,6,7 the seizure origin of fear has also been found to originate from mesial frontal regions,8 occipital,9,10 and parietal11 lobes; besides, there has been no consensus as to its lateralizing significance.12–14 In addition, most evidence on the localization of 
TI - The localization and lateralization of fear aura and its surgical prognostic value in patients with focal epilepsy
JF - Annals of Clinical and Translational Neurology
DO - 10.1002/acn3.51607
DA - 2022-08-01
UR - https://www.deepdyve.com/lp/wiley/the-localization-and-lateralization-of-fear-aura-and-its-surgical-iH68Rb7w0q
SP - 1116
EP - 1124
VL - 9
IS - 8
DP - DeepDyve
ER -