TY - JOUR
AU - Kadam, Tejaswini
AB - We are reporting a rare case of primary gastric synovial sarcoma in a young male. Synovial sarcoma of the stomach is a very rare tumor. The common involved sites of occurrence of synovial sarcomas are upper and lower extremities. In the English literature, only 47 cases of primary synovial sarcoma of stomach have been reported. Spindle-shaped tumor cells are the basic content of synovial sarcomas with varying degrees of epithelial differentiation. The basic classification of synovial sarcoma depends on the histological pattern and the degree of differentiation and it is classified as monophasic, biphasic, and poorly differentiated. Synovial sarcoma presents with classical chromosomal translocation where they form fusion genes of SS18-SSX1, SS18-SSX2, and SS18-SSX4. Fluorescence in situ hybridization (FISH) and reverse transcription polymerase chain reaction (RT-PCR) are the molecular analysis techniques to detect these fusion genes. As the available literature support is limited, the role of adjuvant chemotherapy, radiation therapy, and intra-operative lymphadenectomy is still unclear. However, surgical resection with clear margin is the gold standard treatment.
TI - Primary Gastric Synovial Sarcoma in a Young Male: a Rare Case Report and Review of Literature
JF - Indian Journal of Surgical Oncology
DO - 10.1007/s13193-023-01738-4
DA - 2023-09-01
UR - https://www.deepdyve.com/lp/springer-journals/primary-gastric-synovial-sarcoma-in-a-young-male-a-rare-case-report-i720oRM8cl
SP - 690
EP - 693
VL - 14
IS - 3
DP - DeepDyve
ER -