TY - JOUR AU - Chung, Taylor AB - Background Two-point modified Dixon (mDixon) turbo spin-echo (TSE) sequence provides an efficient, robust method of fat suppression. In one mDixon acquisition, four image types can be generated: water-only, fat-only, in-phase and opposed-phase images. Objective To determine whether PD mDixon TSE water-only and, by proxy, PD in-phase images generated by one acquisition can replace two conventional PD TSE sequences with and without fat suppression in routine clinical MR examination of the knee. Materials and methods This is a retrospective study of 50 consecutive pediatric knee MR examinations. PD mDixon TSE water- only and PD fat-saturated TSE sequences (acquired in the sagittal plane with identical spatial resolution) were reviewed indepen- dently by two pediatric radiologists for homogeneity of fat suppression and detection of intra-articular pathology. Thirteen of the 50 patients underwent arthroscopy, and we used the arthroscopic results as a reference standard for the proton-density fat-saturated and proton-density mDixon results. We used the Kruskal-Wallis rank test to assess difference in fat suppression between the proton- density mDixon and proton-density fat-saturated techniques. We used kappa statistics to compare the agreement of detection of intra-articular pathology between readers and techniques. We also calculated sensitivity, specificity and accuracy between arthros- copy and MR interpretations. TI - Clinical experience with two-point mDixon turbo spin echo as an alternative to conventional turbo spin echo for magnetic resonance imaging of the pediatric knee JF - Pediatric Radiology DO - 10.1007/s00247-019-04349-w DA - 2019-02-06 UR - https://www.deepdyve.com/lp/springer-journals/clinical-experience-with-two-point-mdixon-turbo-spin-echo-as-an-hqQ0X56Ik1 SP - 791 EP - 800 VL - 49 IS - 6 DP - DeepDyve ER -