TY - JOUR
AB -  Showcasing research from Luigi Paduano and co-workers, Department of Chemical Sciences, University of Naples "Federico II", Naples, Italy. Phosphocholine-decorated superparamagnetic iron oxide nanoparticles: defining the structure and probing in vivo applications Superparamagnetic Iron Oxide Nanoparticles (SPIONs) were functionalized through hydrophobic interaction with a biocompatible phosphocholine layer. The in vitro and in vivo study proves the effective applicability of phosphocholinedecorated SPIONs as Magnetic Resonance Imaging (MRI) contrast agents. The versatility of the used functionalization approach is highlighted by introducing onto the SPION's surface a rutheniumbased potential antitumoral drug, named ToThyCholRu. In vitro bioscreens demonstrate the antiproliferative activity of the ToThyCholRu-decorated SPIONs as promising theranostic agents. As featured in: Volume 8 Number 19 21 May 2016 Pages 9871­10456 Nanoscale www.rsc.org/nanoscale ISSN 2040-3364 PAPER Ho Seong Jang et al. Direct observation of the core/double-shell architecture of intense dual-mode luminescent tetragonal bipyramidal nanophosphors See Luigi Paduano et al. Nanoscale, 2016, 8, 10078. www.rsc.org/nanoscale Registered charity number: 207890 
TI - Back cover
JF - Nanoscale
DO - 10.1039/C6NR90104B
DA - 2016-05-12
UR - https://www.deepdyve.com/lp/royal-society-of-chemistry/back-cover-hY7QCnJsTd
SP - 10456
EP - 10456
VL - 8
IS - 19
DP - DeepDyve
ER -