TY - JOUR AU - Gora, Mary Lea AB - OBJECTIVE:To review the role of transdermal nicotine as an aid to smoking cessation.DATA SOURCES:A MEDLINE search was performed that included clinical studies published in English involving transdermal nicotine; references used in those articles were screened for additional published information.STUDY SELECTION:Published clinical trials were reviewed with particular emphasis on controlled trials that evaluated safety and efficacy.DATA SYNTHESIS:Transdermal nicotine therapy has been shown to be a safe and effective pharmacologic aid in a smoking cessation program when used in conjunction with a psychologic or behavior support system. Habitrol, Nicoderm, Nicotrol, and PROSTEP differ in some characteristics (i.e., delivery systems, total nicotine content and amount absorbed, rate of delivery, recommended duration of application); however, the clinical implication of these differences has not been determined.CONCLUSIONS:Transdermal nicotine is effective for patients who are motivated to quit smoking and receive concomitant behavior support. TI - Nicotine Transdermal Systems JF - Annals of Pharmacotherapy DO - 10.1177/106002809302700615 DA - 1993-06-01 UR - https://www.deepdyve.com/lp/sage/nicotine-transdermal-systems-hQ0290m5d9 SP - 742 EP - 750 VL - 27 IS - 6 DP - DeepDyve ER -