TY - JOUR
AU - HOWEL EVANS, W.
AB - GENETIC FACTORS IN THYROID DISEASES F. D. Kitchin & W. Howel Evans 1. Toxic Diffuse Goitre Long-continued investigation has failed to reveal any extrinsic factor of aetiological importance to account for the familial disposition in toxic diffuse goitre, although much has been learnt of the functional disturbance in this disorder. In GENETIC FACTORS IN THYROID a situation of this sort, pedigicc analysis can be expected to show whether genetic influences exert a major part, but in a DISEASES common disease single families or small groups of families provide an unsuitable basis for an investigation of the manner F. D. KTTCHIN M.D. M.R.C.P. of inheritance. Thus Bartels (1941) found slender evidence from many published pedigrees for a dominant mode of W. HOWEL EVANS M.D. M.R.C.P. inheritance, with incomplete penetrance and sex-limitation to women, but because of the uncertainty of the diagnosis and Thyroid CUnic the lack of a control group he considered this material unfit David Lewis Northern Hospital, Liverpool for detailed analysis. In his own observations, derived from Department of Medicine 204 propositi8 with Graves's disease and 21 propositi with University of Liverpool toxic adenoma, the control group consisted of 498 normal propositi who were regarded as representative of 
TI - GENETIC FACTORS IN THYROID DISEASES
JF - British Medical Bulletin
DO - 10.1093/oxfordjournals.bmb.a069815
DA - 1960-05-01
UR - https://www.deepdyve.com/lp/oxford-university-press/genetic-factors-in-thyroid-diseases-gGdz4gupC9
SP - 148
EP - 151
VL - 16
IS - 2
DP - DeepDyve
ER -