TY - JOUR AU - AB - Reactions 410 - 18 Jul 1992 Mania: case report A 29-year-old man with a 5-month history of depressive episodes ingested 30 ml of ’Triaminicol’ (chlorpheniramine 0.4 mg/ml, dextromethorphan 2 mg/ml and phenylpropanolamine 2.5 mg/ml) for a cough and found it resolved his depression but led to his first manic episode. Subsequently, the patient, who had a family history of mood disturbances, ingested 180-480 ml of ’Triaminicol’ to relieve his depression by inducing mania. The patient was hospitalised for bipolar disorder and, on discontinuation of ’Triaminicol’ and administration of lithium and perphenazine, his mania resolved. However, mania recurred 2 months later when, after discontinuing his medication, he once again treated his depression with ’Triaminicol’. Author comment:’ Of the ingredients in Triaminicol, PPA phenylpropanolamine is the most likely to elicit mania . . This patient illustrates the risk of abuse of over-the-counter preparations among individuals predisposed to mania.’ Mendez MF. Mania self-induced with cough syrup. Journal of Clinical Psychiatry 53: 173-174, May 1992 - USA 800143089 0114-9954/10/0410-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved Reactions 18 Jul 1992 No. 410 TI - Antitussives JO - Reactions Weekly DO - 10.2165/00128415-199204100-00009 DA - 2013-01-22 UR - https://www.deepdyve.com/lp/springer-journals/antitussives-g2wDMwnf0L SP - 4 EP - 4 VL - 410 IS - 1 DP - DeepDyve ER -