TY - JOUR AU - Appel, Lawrence J. AB - Response to Let te R to e dito R Response to “The Data Show a U-Shaped Association of Sodium Intake With Cardiovascular Disease and Mortality” 1,2 3–5 Paul K. Whelton and Lawrence J. Appel To the Editor: Dr Graudal’s responses (Na) and cardiovascular disease (CVD) additional concerns regarding the analy- to our commentary do not assuage our yielded significant relationships that sis performed by Graudal et al. Abundant concerns regarding his meta-analysis were consistent with benefits of a reduc - evidence supports the common recom- and the methodological limitations of tion in Na. In contrast to Dr Graudal’s mendation from the US Government, the underlying database. Regarding claim that “these blood pressure tri- American Heart Association, Institute of the issues raised in his letter, the 2004 als provide no support that reduction Medicine, World Health Organization, Institute of Medicine (IOM) cut points of sodium intakes below 2,300 mg/day UK National Institute for Health and for adequate intake (AI) and tolerable is either safe or will result in human Care Excellence (NICE) and other upper intake level (UL) may not be to Dr benefits” the published results indicate organizations to reduce Na intake in the Graudal’s liking but he is not at liberty TI - Response to “The Data Show a U-Shaped Association of Sodium Intake With Cardiovascular Disease and Mortality” JF - American Journal of Hypertension DO - 10.1093/ajh/hpu252 DA - 2015-03-26 UR - https://www.deepdyve.com/lp/oxford-university-press/response-to-the-data-show-a-u-shaped-association-of-sodium-intake-with-g2Xo2bfVEn SP - 426 EP - 427 VL - 28 IS - 3 DP - DeepDyve ER -