TY - JOUR
AU1 - Courtice, F. C.
AU2 - Gunton, R. W.
AB - J. Physiol. (I949) Io8, I42-I56 6I2. iI6 THE THE DETERMINATION OF BLOOD VOLUME IN MAN BY THE AND CARBON MONOXIDE DYE METHODS BY F. C. COURTICE AND R. W. GUNTON From the University Laboratory of Physiology, Oxford (Received 14 February 1948). The blood volume in man has been determined one of largely two by methods, the dilution of a known volume of carbon monoxide in the or corpuscles of a known amount of in dye the Carbon monoxide was plasma. first used for this purpose in the human subject Haldane & Smith by The (1900). general for the procedure administration of the carbon monoxide is still in principle the same as that used these but the by investigators, analytical methods for blood determining carbon monoxide have in improved accuracy. Haldane employed the carmine titration method which has certain dis- and is not advantages, suitable for low concentrations in very the blood. Van & Salvesen introduced Slyke (1919) a method the use of the van involving and Slyke apparatus, further in this improvements have been technique made (cp. Peters & van Slyke, 1932). More recently, Scholander & Roughton (1943) have evolved an accurate and convenient method for the determination of 
TI - The determination of the blood volume in man by the carbon monoxide and dye methods
JF - The Journal of Physiology
DO - 10.1113/jphysiol.1949.sp004317
DA - 1949-01-15
UR - https://www.deepdyve.com/lp/wiley/the-determination-of-the-blood-volume-in-man-by-the-carbon-monoxide-g129FdIiBk
SP - 142
EP - 156
VL - 108
IS - 2
DP - DeepDyve
ER -