TY - JOUR
AU1 - Mizera, L.
AU2 - Gossrau, G.
AU3 - Hummel, T.
AU4 - Haehner, A.
AB - Antje Haehner Background: There is some evidence suggesting that analgesics have E-mail: antje.haehner@uniklinikum-dresden. de an impact on human chemosensory function, especially opioids and cannabinoids are known to interfere with olfactory function. However, Funding sources largely unknown is the effect of a long-term use of analgesics on the None. intranasal trigeminal system so far. Here, we investigated olfactory function and the perception of intranasal trigeminal stimuli in pain Conflicts of interest patients with long-term use of analgesics compared to age-matched None declared. healthy controls. Methods: For this purpose, a psychophysical approach was chosen to Accepted for publication measure these sensory functions in 100 chronic pain patients and 95 2 May 2016 controls. Olfactory testing was performed using the ‘Sniffin’ Sticks’ test kit, which involves tests for odour threshold, odour discrimination and doi:10.1002/ejp.903 odour identification. Further, participants were asked to rate the intensity of trigeminal stimuli by using a visual analogue scale. Results: We observed that the chronic use of pain medication was associated with significantly reduced perception of intranasal trigeminal stimuli and olfactory function compared to age-matched controls without intake of analgesics. Results indicate that non-opioid and opioid drugs, or a combination of both did not differ in their effects 
TI - Effects of analgesics on olfactory function and the perception of intranasal trigeminal stimuli
JF - European Journal of Pain
DO - 10.1002/ejp.903
DA - 2017-01-01
UR - https://www.deepdyve.com/lp/wiley/effects-of-analgesics-on-olfactory-function-and-the-perception-of-fgTrK0eDk5
SP - 92
EP - 100
VL - 21
IS - 1
DP - DeepDyve
ER -