TY - JOUR
AU - 
AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 283, NO. 25, pp. 17341–17350, June 20, 2008 © 2008 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in the U.S.A. The Human Hyaluronan Receptor for Endocytosis (HARE/Stabilin-2) Is a Systemic Clearance Receptor for Heparin Received for publication, December 19, 2007, and in revised form, April 14, 2008 Published, JBC Papers in Press, April 22, 2008, DOI 10.1074/jbc.M710360200 Edward N. Harris, Janet A. Weigel, and Paul H. Weigel From the Department of Biochemistry and Molecular Biology, and The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190 The hyaluronic acid receptor for endocytosis (HARE; also proteins and receptors, and has many functions, including its designated Stabilin-2) mediates systemic clearance of hyaluro- roles as an anti-coagulant and as a co-receptor for some growth nan and chondroitin sulfates from the vascular and lymphatic factors (1, 2). Hep is a highly prescribed drug in surgical patients circulations. The internalized glycosaminoglycans are degraded and those at risk for thromobosis. The genes and metabolic in lysosomes, thus completing their normal turnover process. pathway for Hep biosynthesis in mast cells are understood rea- Sinusoidal endothelial cells of human liver, lymph 
TI - The Human Hyaluronan Receptor for Endocytosis (HARE/Stabilin-2) Is a Systemic Clearance Receptor for Heparin
JF - Journal of Biological Chemistry
DO - 10.1074/jbc.m710360200
DA - 2008-06-01
UR - https://www.deepdyve.com/lp/unpaywall/the-human-hyaluronan-receptor-for-endocytosis-hare-stabilin-2-is-a-fTAjk1Mfy0
DP - DeepDyve
ER -