TY - JOUR
AU - Partridge, M W
AB - THE PARTITION CHROMATOGRAPHY OF ALKALOIDS PART III.-THE ALKALOIDS OF PUNICA GRANATUM BY J. CHILTON AND M. W. PARTRIDGE From the University, Nottingham. Received June 21, 1950. THE systematic study of anthelmintics appears to have been hitherto totally incommensurate with the importance of helminthiasis, which in various forms affects an estimated 800 million people'. In particular. tradiltional remedies have been subjected to little critical examination. The difficulties encountered in the in vitro culture of many parasitic worms2 and in testing anthelmintics are amongst the important reasons for this. Recently progress has been made in the development of in vitro tests, one of which3 employs the liver fluke and would appear to be of value in estimating the comparative activities of anthelmintics. particularly against trematode and cestode parasites. Preparations of the root of Punica Granatum have long been in use as taenifuges and the so-called " pelletierine tannate " of the Pharma- eopceia is an example of such a preparation which is intended to contain the active constituents of this drug. A thorough search of the literature has revealed only the work of von Schroeder' in 1884, who showed that pelletierine was toxic to tapeworms; this alkaloid has, as a consequence, 
TI - The Partition Chromatography of Alkaloids: Part III.—The Alkaloids ofPunica Granatum
JO - Journal of Pharmacy and Pharmacology
DO - 10.1111/j.2042-7158.1950.tb13001.x
DA - 1950-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-partition-chromatography-of-alkaloids-part-iii-the-alkaloids-fOHprKK0sS
SP - 784
EP - 795
VL - 2
IS - 1
DP - DeepDyve
ER -