TY - JOUR
AU - Hindmarsh, Peter C.
AB - Objective: To investigate the relationship between levels of insulin-like growth factors 1 and 2 (IGF-1, IGF-2), and insulin-like growth factor binding protein 3 (IGFBP-3) in antenatal maternal serum and in fetal cord blood at delivery. Methods: Prospective cohort study of 1650 low-risk Caucasian women in a University teaching hospital in London. Statistical analysis was performed using commercial software (SPSS for Windows, version 6.1, SPSS, Chicago, Illinois, USA), with p < 0.05 as significant. Maternal IGF 1, IGF 2 and IGF BP-3 were assessed on maternal blood at booking and in fetal blood by cord blood analysis at delivery. Cord pH was also recorded. Results: There was no significant correlation between maternal IGF-1, IGF-2, or IGFBP-3 levels and fetal acidosis. However, a significant correlation does exist between cord IGF-1 levels and fetal acidosis. Conclusion: Fetal cord IGF-1 has a significant correlation with fetal acidosis at delivery.
TI - Maternal and fetal insulin-like growth factors 1 and 2 (IGF-1, IGF-2) and IGF BP-3, and their relationship to fetal acidosis at delivery
JF - Journal of Perinatal Medicine
DO - 10.1515/JPM.2004.139
DA - 2004-09-01
UR - https://www.deepdyve.com/lp/de-gruyter/maternal-and-fetal-insulin-like-growth-factors-1-and-2-igf-1-igf-2-and-fNAChNl4rJ
EP - 421
VL - 32
IS - 5
DP - DeepDyve
ER -