TY - JOUR AU - Simmonds, Peter AB - [International standardization and coordination of the nomenclature of variants of hepatitis C virus (HCV) is increasingly needed as more is discovered about the scale of HCV-related liver disease and important biological and antigenic differences that exist between variants. Consistency in numbering is also increasingly required for functional and clinical studies of HCV. For example, an unambiguous method for referring to amino acid substitutions at specific positions in NS3 and NS5B coding sequences associated with resistance to specific HCV inhibitors is essential in the investigation of antiviral treatment. Inconsistent and inaccurate numbering of locations in DNA and protein sequences is becoming a problem in the HCV scientific literature.] TI - Hepatitis C: Nomenclature and Numbering of the Hepatitis C Virus DA - 2009-01-01 UR - https://www.deepdyve.com/lp/springer-journals/hepatitis-c-nomenclature-and-numbering-of-the-hepatitis-c-virus-f33yC0TXJy DP - DeepDyve ER -