TY - JOUR
AU1 - Abed, Ahmed
AU2 - Kavvadas, Panagiotis
AU3 - Chadjichristos, Christos
AB - Kidneys are highly complex organs, playing a crucial role in human physiopathology, as they are implicated in vital processes, such as fluid filtration and vasomotor tone regulation. There is growing evidence that gap junctions are major determinants of renal physiopathology. It has been demonstrated that their expression or channel activity may vary depending on physiological and pathological situations within distinct renal compartments. While some studies have focused on the role of connexins in renal physiology, our knowledge regarding the functional relevance of pannexins is still very limited. In this paper, we provide an overview of the involvement of connexins, pannexins and their channels in various physiological processes related to different renal compartments.
TI - Functional roles of connexins and pannexins in the kidney
JF - Cellular and Molecular Life Sciences
DO - 10.1007/s00018-015-1964-5
DA - 2015-06-17
UR - https://www.deepdyve.com/lp/springer-journals/functional-roles-of-connexins-and-pannexins-in-the-kidney-esWK20t0eH
SP - 2869
EP - 2877
VL - 72
IS - 15
DP - DeepDyve
ER -