TY - JOUR AU - AB - Background: Hepatitis E virus (HEV) is one of the important zoonotic diseases with a worldwide distribution. The main objective of this study was to assess the prevalence and phylogenetic analysis of HEV in Vietnam. Pig blood and fecal pooled samples were used to determine for the prevalence of HEV. We evaluated the true prevalence (TP) of HEV from apparent prevalence (AP) by taking into account the sensitivity and speci city of diagnostic tests using a Bayesian approach. For phylogenetic analysis, the data compared with worldwide HEV reference strains illustrating all eight genotypes (G1-G8) which were identi ed in previous study. Results: A total of 475 sera samples were collected at slaughterhouses from ve provinces. The AP of HEV was 58.53% (95% CI: 53.95–62.70) while the TP was slightly higher (59.96%, 95% credible interval: 54.49–65.41). A total of 19 Vietnamese strains were isolated from 1 strain in Hanoi, 5 strains in Dak Lak, 7 strains in An Giang, 4 strains in Son La and 2 strains in Nghe An. The phylogenetic tree demonstrated that 19 Vietnamese strains were clustered into HEV 3 and 4 among 8 genotypes. Conclusions: This study provided evidence that HEV is circulating in domestic pigs TI - Prevalence and Phylogenetic Analysis of Hepatitis E Virus in Pigs in Vietnam DO - 10.21203/rs.3.rs-27992/v1 DA - 2020-05-27 UR - https://www.deepdyve.com/lp/unpaywall/prevalence-and-phylogenetic-analysis-of-hepatitis-e-virus-in-pigs-in-ek2ggzG1pO DP - DeepDyve ER -