TY - JOUR
AB - Inpharma 1275 - 17 Feb 2001 Wait-and-see approach ‘feasible’ in AOM Delayed prescribing of antibacterials ‘is feasible’ in the management of paediatric patients with acute otitis media (AOM), as the benefits of immediate antibacterial therapy are seen mainly after the first 24 hours when symptoms are already resolving, say researchers from the UK. In this multicentre, open-label study, 315 patients (aged 6 months to 10 years) with AOM were randomised to receive immediate antibacterial treatment (n = 151) or delayed antibacterial treatment (i.e. asked to wait 72 hours after seeing the doctor before considering using the prescription). Patients who received immediate, compared with delayed, antibacterial treatment had significantly shorter durations of ear discharge (0.56 vs 1.21 days), earache (2.56 vs 3.57 days), night-time disturbance (1.64 vs 2.35 days) and crying (1.54 vs 2.23 days), and consumed a significantly smaller amount of paracetamol [acetaminophen] (1.69 vs 2.28 spoons/day). ‘Modest symptomatic benefit’ The researchers comment that ‘most of these differences, however, probably reflect modest symptomatic benefit’. They add that ‘the reduction in paracetamol use occurred only after the first 24 hours after seeing the doctor, when children were less distressed and the illness was starting to settle’. There were no significant 
TI - Wait-and-see approach `feasible' in AOM
JF - Inpharma Weekly
DO - 10.2165/00128413-200112750-00034
DA - 2013-02-09
UR - https://www.deepdyve.com/lp/springer-journals/wait-and-see-approach-feasible-in-aom-eWf5j5jwdo
SP - 14
EP - 14
VL - 1275
IS - 1
DP - DeepDyve
ER -