TY - JOUR
AU1 - Kara, Hakan
AU2 - Sönmez, Said
AU3 - Bağbudar, Sidar
AU4 - Güllüoğlu, Mine
AU5 - Başaran, Bora
AB - Non-sebaceous lymphadenoma is a sporadic benign tumor of salivary glands. Histopathologic and immunohistochemical properties, diagnostic criteria, and theories for the histologic origin of the disease have been defined and well-discussed in the literature. However, none of the cases showed malignant transformation to date. We reported a case of 54 years old female patient with a right preauricular mass. Magnetic resonance imaging demonstrated a 2 cm, well-defined contrast-enhanced mass in the right parotid gland. Fine needle aspiration cytology was undiagnostic but suspicious for malignancy. Total parotidectomy with facial nerve preservation was done. In the histopathological examination, non-sebaceous lymphadenoma regions and malignant cells with abundant cytoplasm, large vesicular nuclei, and prominent nucleoli, which occupied approximately 70% of the mass, were seen. The diagnosis was undifferentiated carcinoma arisen from non-sebaceous lymphadenoma. Adjuvant radiotherapy was given. No recurrence was detected during ten months of follow-up. This case is the first case of a malignancy developed from non-sebaceous lymphadenoma.
TI - Malignant Transformation of Parotid Gland Non-sebaceous Lymphadenoma: Case Report and Review of Literature
JF - Head and Neck Pathology
DO - 10.1007/s12105-020-01133-3
DA - 2020-12-29
UR - https://www.deepdyve.com/lp/springer-journals/malignant-transformation-of-parotid-gland-non-sebaceous-lymphadenoma-eGc0VjsmK5
SP - 1123
EP - 1128
VL - 14
IS - 4
DP - DeepDyve
ER -