TY - JOUR AU - Rosenthal, Norman E. AB - of Seasonal Affective Disorder Neurobiology and Phototherapy Robert G. Skwerer* 1 Frederick M. Connie C. Jacobsen, * Duncan,† * * David A. * Lawrence Karen A. * Paul A. Kelly, Sack, Tamarkin, Gaist, * and Norman E. Rosenthal* Siegfried Kasper, *Clinical Branch and and Psychobiology †Laboratory of Psychology National Institute Mental Health, Psychopathology, of Bethesda, Maryland The of the biochemical basis of seasonal affective disorder and investigation (SAD) is a new field. As with of ex- any body light therapy knowledge undergoing rapid the are and at times even pansion, data, though interesting, incomplete conflicting. In this we to and the information avail- attempt organize synthesize currently paper, able a and understandable form. into coherent The of SAD has been described elsewhere al., syndrome (Rosenthal et 1984; this Features of SAD include marked in Terman, issue). level, changes energy ap- and mood. Its to has been ex- petite, activity, weight, response bright light sleep, this documented al., 1984, the tensively (Rosenthal et issue). However, biological basis for these diverse and remains as does unclear, psychological biological changes the mechanism of the effects of Theories have been advanced antidepressant light. to the dramatic effects of most the &dquo;melatonin explain phototherapy, TI - Neurobiology of Seasonal Affective Disorder and Phototherapy JF - Journal of Biological Rhythms DO - 10.1177/074873048800300204 DA - 1988-06-01 UR - https://www.deepdyve.com/lp/sage/neurobiology-of-seasonal-affective-disorder-and-phototherapy-eE85ODk0kp SP - 135 EP - 154 VL - 3 IS - 2 DP - DeepDyve ER -