TY - JOUR AB - Br. J. Surg. 1993, Vol. 80. September. A selection ,from the August issue uf the American journal. 1210-121 1 relatzve smsztz7iity of islet, iuholr panirras, and romposzte Use of gene therapy to induce izzcln y-zslet trrcnspkints to rrturrent nutozmmnn~t~. human-mouse xenogeneic chimerism Methods. Atutrly dzabetzr (BB-Ar) BB role served ns reizpients of ~iasri~lanzed panrrriis, intraportal (IPo) or rum1 caj)sular (KCJ idrt transplrints, or vnstulamzrd romposzte Ira J. Fox, MD, Eleni Athan, PhD, Jon Fisher, AB, kidnqy-zrh ,yajs from RK-IIR or HB-I)P donors. C;r@ B. Timothy Baxter, MD, Silvio Podda, MD, and Junrtzon was assessed by dad) blood glu(o~r hurl, and the ChristineRichardson, MA, Omaha, hW)., nndNe7u York, N. I.: oulrowie was ronJirmed on hzstolop rxaminntzon. Cjrlo- spomne 5 rng/kg/day zntrnmucrularl) 7uac ndmznzcterrd to Background. Bone tn~crroy07ii lrancplantation (BMT) line bern arcrcr 11s pJfprt on rerurrrnt J-i~ll inprj. urrd an the kiborcctory to 07ier(omc the ammuno1opi barmen to Results. BB-DP pnnrrrasec de~~lop~ii recurrent nuto- x~~notrccnc~lantntinn and rrcults zn rhzmmtin and cf)r(i$i zmrnunzlj in 55% of rnsrs; cyrlotpomnr afJorded rompletr tolerance to clonor antigrnc zn lrthnlly zrrudaatrd miir. protection 2f mazntninrd. hzbplry reszstantr 7uns transplnntrd Clznzrally, BMI' rarmrs Lhr roncidPmbC mekr of gruj-urrrus- 7112th 23 of 23 BB-DR pancreas ,y@; ho7umq TI - Surgery Abstracts JF - British Journal of Surgery DO - 10.1002/bjs.1800800950 DA - 1993-09-01 UR - https://www.deepdyve.com/lp/oxford-university-press/surgery-abstracts-e1lPlDbOw3 SP - 1210 EP - 1211 VL - 80 IS - 9 DP - DeepDyve ER -