TY - JOUR
AU - Mora, Carlos A.
AB - A clear understanding of the origin and role of the different subtypes of the B cell lineage involved in the activity or remission of multiple sclerosis (MS) is important for the treatment and follow-up of patients living with this disease. B cells, however, are dynamic and can play an anti-inflammatory or pro-inflammatory role, depending on their milieu. Depletion of B cells has been effective in controlling the progression of MS, but it can have adverse side effects. A better understanding of the role of the B cell subtypes, through the use of surface biomarkers of cellular activity with special attention to the function of memory and other regulatory B cells (Bregs), will be necessary in order to offer specific treatments without inducing undesirable effects.
TI - Continued dysregulation of the B cell lineage promotes multiple sclerosis activity despite disease modifying therapies
JO - F1000Research
DO - 10.12688/f1000research.74506.3
DA - 2023-08-01
UR - https://www.deepdyve.com/lp/pubmed-central/continued-dysregulation-of-the-b-cell-lineage-promotes-multiple-dxrVugwCsM
VL - 10
IS - 
DP - DeepDyve
ER -