TY - JOUR
AU1 - Spielman, Andrew
AU2 - Shih, Chien-Ming
AB - JID 1994; 169 (April) Correspondence tients receiving ceftriaxone [Rocephin], and bloodstream infec­ patients are still being followed. and 15 have been lost to tions associated with intravenous catheters." follow-up. The 79% referred to in the report is the percentage of patients It is important to note that sludge formation associated with hospitalized, not the percentage of patients receiving ceftriax­ Rocephin therapy has been both rare and transient (it is esti­ one who developed symptoms of gallbladder disease. Patients mated that >20 million patients have been treated with Ro­ were hospitalized for the following reasons: treatment of sus­ cephin). When Rocephin is discontinued, the condition resolves pected Lyme disease, drug-induced complications including but uneventfully. Our package insert reference to "conservative not limited to symptoms of gallbladder disease, and sepsis asso­ management" reflects our message that sludge formation is a ciated with intravenous catheters. transient phenomenon. It suggests that surgical removal of the On the basis of the initial telephone survey, a retrospective gallbladder may be unnecessary and the patient should be man­ study was done that identified 1352 patients discharged from aged via observation. the hospital with a primary or secondary diagnosis of Lyme dis­ Ceftriaxone has not been shown 
TI - Reply
JF - The Journal of Infectious Diseases
DO - 10.1093/infdis/169.4.938
DA - 1994-04-01
UR - https://www.deepdyve.com/lp/oxford-university-press/reply-dn7Wjsfii0
SP - 938
EP - 938
VL - 169
IS - 4
DP - DeepDyve
ER -