TY - JOUR
AU1 - Singh, Shamer
AU2 - Sanyal, A.K.
AB - Acia anal. 89: 121 133 (1974) D epartm ent of Anatomy, In stitu te of Medical Sciences, Bañaras Hindu University, Varanasi, India Abnormal patterns of ossification in the hands of foetuses produced by cyclophosphamide administration to pregnant rats S h a m e k S in g h a n d A . K . S a n y a l I n tr o d u c tio n Cyclophosphamide, a recently synthesized polyfunctional alkylating agent belonging to the nitrogen m ustard group, is widely used in cancer chemotherapy [ChauBE c( h!., 1967] because of its low toxicity and higher therapeutic index. Its cytotoxic effect, i.e., interfering with the proeess of eell division in the rapidly proliférât ing t issues, has been show n to be teratogenic in various laboratory animals, e.g.. chicks [Gerlinger et al., 1963: Singh et al.. 1971: Singh and Gupta. 1972]: rabbits [Gf.rlingf.r. 1964: F ritz and Hess, 19711: rats [Wilson, 1964: Krf.ybic. 1965: K reybic and Schmidt, 1967; Chau be ei al.. 1967: Chaube and Murphy, 1968: Singh. 1971; Singh and Sanyal. 1972; Singh et al., 1974J; mice [Shoji and Olizu, 1965; Gibson and B ecker, 1968; Gebhardt. 19701 and possibly in the 
TI - Abnormal patterns of ossification in the hands of foetuses produced by cyclophosphamide administration to pregnant rats
JF - Cells Tissues Organs
DO - 10.1159/000144276
DA - 1974-01-01
UR - https://www.deepdyve.com/lp/karger/abnormal-patterns-of-ossification-in-the-hands-of-foetuses-produced-by-dY9xRoEvxW
SP - 121
EP - 133
VL - 89
IS - 1
DP - DeepDyve
ER -