TY - JOUR AU - Praag, H. AB - Drugs 43 (Suppl. 2): 55·57, 1992 0012-666 7/92/0200.0055/$1.50/0 © Adis International Limited. All rights reserved. DRSUP3408 H.M. van Praag Department of Psychiatry, Albert Einstein College of Medicine/Montefiore Medical Center, New York, New York, USA ering compounds with a selective action on the There have been remarkable advances in our understanding of the complexity of the seroton­ serotonergic system. As it eventuates now, the serotonin reuptake inhibitors have a range of in­ ergic system during the last 6 to 8 years. It was dications in addition to depression, including panic known for many years that serotonergic neurons disorder, obsessive-compulsive disorder, and eat­ are few in number, and are narrowly distributed ing disorders. within particular areas of the brain, while the sero­ At this point I would like to briefly address sev­ tonergic axons branch out over large domains of eral issues that have not been discussed today or the brain, and the brain stem and spinal cord. that have been mentioned only superficially. Firstly, However, the discovery of the multiplicity of sero­ I would like to amplify the comment made earlier tonergic receptors - to date we know of the exist­ by Professor Leonard, regarding the interaction of ence of TI - Concluding Remarks JF - Drugs DO - 10.2165/00003495-199200432-00009 DA - 2012-11-30 UR - https://www.deepdyve.com/lp/springer-journals/concluding-remarks-dWloEhikj3 SP - 55 EP - 57 VL - 43 IS - 2 DP - DeepDyve ER -