TY - JOUR
AU - Koroma, Mohamed
AB - BackgroundThe AOAC Expert Review Panel (ERP) approved a method for the quantification of folic acid in various dietary supplement dosage forms containing tablets, 2-piece capsules, powder drinks, softgels, and gummies with First Action Official MethodSM status.ObjectiveThe previously published method summarized a single-laboratory validation with parameters of linearity, LOD, LOQ, repeatability, recovery, specificity, and system suitability. Based on the request from the ERP, the recovery test for the gummies has been reperformed with a revised procedure.MethodsDetermination of Folic Acid in Various Dietary Supplement Dosage Forms UPLC/PDA.ResultsThe recovery range of 94.6–106.5% was achieved by spiking 20, 50, and 80% in the gummy samples. Other adjustments or clarification of the method and minor typos were also addressed.ConclusionAfter the revised method, report, and results were analyzed and discussed, the ERP adopted the method and provided recommendations for achieving Final Action status.HighlightsThe revised method meets the requirements of Standard Method Performance Requirement (SMPR®) 2022.002.
TI - Determination of Folic Acid in Various Dietary Supplement Dosage Forms by UPLC/PDA: Single-Laboratory Validation, First Action 2024.09
JO - Journal of AOAC INTERNATIONAL
DO - 10.1093/jaoacint/qsaf014
DA - 2025-06-03
UR - https://www.deepdyve.com/lp/oxford-university-press/determination-of-folic-acid-in-various-dietary-supplement-dosage-forms-dECuu2SLLA
SP - 658
EP - 659
VL - 108
IS - 4
DP - DeepDyve
ER -