TY - JOUR
AU - 
AB - In this paper some chalcones (C1-C8) are prepared based on the reaction of one mole of substituted acetophenone with one mole of substituted benzaldehydes in the presence of (40%) sodium hydroxide as a base. Pyrazolines (P1–P8) are prepared from the reaction of chalcones (C1-C8) with hydrazine hydrate. Isoxazoline (I1-I8) is prepared from the reaction of chalcones (C1-C8) with hydroxyl amine hydrochloride in the presence of (10%) sodium hydroxide as a base. These compounds are characterized by using various physical and spectral methods. The compounds are screened for their in vitro antibacterial activity using gram- positive bacteria and gram-negative bacteria. Several derivatives of pyrazolines and isoxazolines are produced well to moderate activities against number of bacteria. Key words: Chalcones, Pyrazolines, Isoxazolines, Antibacterial. Introduction: Chalcones are α, β-unsaturated insecticidal agents and considerable ketone containing the reactive attention has been given to this class [9- ketoethylenic group –CO-CH=CH-. 15]. In addition, pyrazolines have played These are coloured compounds because a crucial part in the development of of the presence of the chromophore - theory in heterocyclic chemistry and CO-CH=CH-, which depends on the also used extensively in organic presence of other auxochromes. synthesis [16-17]. Different methods are available for the Isoxazoline represents 
TI - Synthesis and Characterization of Some New Pyrazoline and Isoxazoline Derivatives as Antibacterial Agents
JF - Baghdad Science Journal
DO - 10.21123/bsj.13.3.568-577
DA - 2016-09-04
UR - https://www.deepdyve.com/lp/unpaywall/synthesis-and-characterization-of-some-new-pyrazoline-and-isoxazoline-ckbSG5Bk1h
DP - DeepDyve
ER -