TY - JOUR AU - Rutherford, Ian M. AB - Letters to the Editor The Effect of Tocopherol on High- density Lipoprotein Cholesterol To the Editor:—As others have ob­ All were within 10% of their ideal weight to side-by-side treatments with heparin- served, the finding of Hermann and his for height. Six subjects (2,3,6,7,9,11) MnCl and sodium phosphotungstate- associates that large doses of tocopherol had histories of coronary heart disease, MgCl to precipitate the lipoproteins can increase the percentage of plasma but none were either troubled by it or other than HDL. Both methods were being treated for it at the time of the performed as described by Lopes-Virella cholesterol in high density lipoproteins experiment. Blood was drawn from each and colleagues except that in both pre­ (HDL) at the expense of other lipopro­ subject after an overnight fast before the cipitations the samples were allowed to teins could have important implications trial and after 30 days of treatment with sit overnight at 4°C after addition of the for programs designed to prevent coro­ synthetic D,L-alpha tocopherol acetate, reagents and before centrifugation. The nary heart disease. As a preliminary to 600 mg per day in divided doses at meal­ supernatant solutions were assayed for a controlled study of the TI - The Effect of Tocopherol on High-density Lipoprotein Cholesterol JF - American Journal of Clinical Pathology DO - 10.1093/ajcp/76.6.843 DA - 1981-12-01 UR - https://www.deepdyve.com/lp/oxford-university-press/the-effect-of-tocopherol-on-high-density-lipoprotein-cholesterol-cX6QMmfgvf SP - 843 EP - 844 VL - 76 IS - 6 DP - DeepDyve ER -