TY - JOUR AU - Hosseini, Hamid AB - ARTICLE A Miniature Shock Wave Driven Micro-Jet Injector for Needle-Free Vaccine/Drug Delivery 1 1 2 Nithin Battula, Viren Menezes, Hamid Hosseini Department of Aerospace Engineering, Indian Institute of Technology Bombay, Powai, Mumbai, India Department of Bioelectrics, Institute of Pulsed Power Science, Kumamoto University, Kumamoto 860-8555, Japan; telephone: þ81-96-342-3963; fax: þ81-96-342-3818; e-mail: hosseini@kumamoto-u.ac.jp network, which can be exploited for a quick dissemination of the injected drug with minimal systemic exposure. The needle-based ABSTRACT: This article presents a miniature shock wave driven micro-jet generator to deliver liquid drugs into human skin, to a drug administration into skin can be extremely painful for the controlled depth, with minimal invasion. The device can release the patients, besides the concerns of contamination and disposal. vaccine/drug to the depth of dermal blood vessels, without Alleviation of fear of needles and the associated trauma has been the breaching much of the microcirculation system of dermis. The drug main motivation for the development of needle-free, subcutaneous delivery technique is needle-free, which can reduce pain, trauma, delivery systems for the transfer of pharmaceutical agents into skin and contamination besides minimal dosage and systemic exposure. The device can also be used to deliver liquid or colloidal drugs into (Arora TI - A miniature shock wave driven micro‐jet injector for needle‐free vaccine/drug delivery JF - Biotechnology and Bioengineering DO - 10.1002/bit.26016 DA - 2016-11-01 UR - https://www.deepdyve.com/lp/wiley/a-miniature-shock-wave-driven-micro-jet-injector-for-needle-free-cRGY0mH6Wb SP - 2507 EP - 2512 VL - 113 IS - 11 DP - DeepDyve ER -