TY - JOUR AU - Guerne, Pierre-André AB - Calcium pyrophosphate dihydrate deposition disease is a common and potentially severe metabolic arthropathy. Early disease (in patients ≤ 60 years old) requires a search for one of the associated metabolic conditions, particularly hemochromatosis. Treatment is primarily symptomatic (no drug is known to prevent the progression of articular destruction). Nonsteroidal anti-inflammatory drugs and intra-articular or systemic glucocorticoids (in small amounts if use is prolonged) are the most useful treatments. Colchicine can be effective to treat recurring pseudogout, and magnesium can be effective on a preventive basis. Methotrexate showed interesting effectiveness in a small, uncontrolled series, and it can be used in the event of failure of the other treatments. TI - Treating difficult crystal pyrophosphate dihydrate deposition disease JO - Current Rheumatology Reports DO - 10.1007/s11926-008-0037-2 DA - 2008-10-24 UR - https://www.deepdyve.com/lp/springer-journals/treating-difficult-crystal-pyrophosphate-dihydrate-deposition-disease-cOygaOFoH0 SP - 228 EP - 234 VL - 10 IS - 3 DP - DeepDyve ER -