TY - JOUR AU1 - Willcox, Mark D. P. AB - 1040-5488/09/8605-0415/0 VOL. 86, NO. 5, PP. 415–419 OPTOMETRY AND VISION SCIENCE Copyright © 2009 American Academy of Optometry FEATURE ARTICLE ON LINE Soft Contact Lens Disinfection Solution Efficacy: Clinical Fusarium Isolates vs. ATCC 36031 Emma B. H. Hume*, Judith Flanagan*, Simin Masoudi , Hua Zhu*, Nerida Cole*, and Mark D. P. Willcox* ABSTRACT Purpose. To compare the disinfecting efficacy of five soft contact lens multipurpose disinfection solutions (MPDS) against Fusarium solani clinical isolates and the ISO standard ATCC 36031 strain. Methods. Three commercially available and two recalled MPDS were tested using the ISO/CD 14,729 stand-alone test for contact lens care products against 10 ocular isolates of F. solani and the ATCC 36031 strain. The effect of filtering the fungal suspension before incubating in MPDS was also tested. An average log reduction in colony forming units at the manufacturer’s minimum recommended disinfection time was determined and compared with criteria for stand-alone disinfection products for each MPDS against each strain. Results. No difference between filtered and unfiltered fungal suspensions was observed for the ISO standard, whereas in one MPDS the representative clinical isolate showed significantly increased resistance when unfiltered. All but one solution met the stand-alone criteria of 1.0-log reduction of TI - Soft Contact Lens Disinfection Solution Efficacy: Clinical Fusarium JF - Optometry and Vision Science DO - 10.1097/OPX.0b013e31819fa239 DA - 2009-05-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/soft-contact-lens-disinfection-solution-efficacy-colon-clinical-cAPQq33xz1 SP - 415 EP - 419 VL - 86 IS - 5 DP - DeepDyve ER -