TY - JOUR
AU1 - Serke, S.
AB - Intensive Care Med (1999) 25: 901±902 ED ITO R IA L Ó Springer-Verlag 1999 S. Serke Hematopoietic growth factors as an adjunct for neutropenic patients in the ICU: still a controversial issue will substantially alter the clinical course. Although no Accepted: 28 June 1999 published data are available to prove this hypothesis, it has been speculated that interventional G-CSF or GM- S. Serke ( ) CSF could even contribute to deterioriation of the neu- Virchow-Klinikum, Medizinische Fakultät der Humboldt- tropenic patient with pneumonia, as particularly GM- Universität zu Berlin, Medizinische Klinik und Poliklinik, CSF increases the expression of vascular adhesion mole- Augustenburger Platz 1, D-13 353 Berlin, Germany Tel.: + 49-30-45053233 ´ Fax: + 49-30-45 05 39 14 cules on neutrophils. However, the clinical efficacy of G-CSF has been shown for non-cancer patients with pneumonia in one study including 756 patients [13]. The prognosis of the neutropenic cancer patient admit- There are, however, well-defined subpopulations of can- ted to ICU for respiratory, hepatic or renal failure or cer patients for which G-CSF or GM-CSF therapy hemodynamic instability is dismal. Only about 15.% of should not be a matter of discussion, even in the setting these patients will survive the 
TI - Hematopoietic growth factors  as an adjunct for neutropenic patients  in the ICU: still a controversial issue
JF - Intensive Care Medicine
DO - 10.1007/s001340050980
DA - 1999-09-15
UR - https://www.deepdyve.com/lp/springer-journals/hematopoietic-growth-factors-as-an-adjunct-for-neutropenic-patients-in-c0lwq2YCyF
SP - 901
EP - 902
VL - 25
IS - 9
DP - DeepDyve
ER -